Facilities

The Kymos Group is an European CRO made up of three sites with 14 laboratory departments, 170 highly trained experts and 5,000 m2 worth of facilities and top-of-the-line instruments. Our GMP/GLP-certified bioanalytical and CMC services are carried out by the following laboratory teams:

  • Analytical Development and Validation
  • Bioanalysis of Small Molecules (aka Mass Spec and Permeation)
  • Bioanalysis of Large Molecules (aka Immunology)
  • Bioanalysis of Oligonucleotides
  • Quality Control of Small Molecules
  • Quality Control of Large Molecules (aka Biopharmaceutical testing)
  • Elemental Analysis
  • Microbiology
  • Stabilities
  • Quality Assurance

In addition to our main laboratories, we are equipped with adjacent facilities for weighting, sample preparation and processing; a combined 100m3 of SCADA-monitored sample storage chambers under all ICH climatic conditions including standard and IVb zones, back-up room, refrigerated conditions, -20ºC freezers and -80ºC ultra-freezers; a microbiology cleanroom for aseptic testing and sample preparation; a containment room for work under O.E.L. Category 4 with high-potency drugs such as hormones, antibiotics or cytotoxins; a radioactivity laboratory to work with Iodine-125; purified water and technical-gas plants; emergency power generators; a fireproof data center for communication and software servers, data storage and back-up systems; as well as offices, meeting rooms, cafeteria and general facilities.

Prolytic

Prolytic Germany

Kymos

Kymos Barcelona

Pharmaprogress

Our Equipment

Mass spectrometry

  • AB SCIEX LC-MS/MS API 3.200 (1), 4.000 (6), 5.500 Qtrap (2), 6.500 Plus (2) and 6.500 Plus QTRAP (1)
  • Qtof Xevo G2-S with BiopharmaLynx and MaxEnt mass spectrometer
  • ICP/MS Agilent 7.700 and 7.800 (2) and digestion system Milestone Ultrawave (2)
  • LC-MS/MS Infinity with MS 6491 Agilent (2)
  • GC-MS Agilent
  • Orbitrap Exploris™ 120 Mass Spectrometer

Liquid chromatography

  • HPLC Alliance Waters and Agilent 1100, 1200, 1260 (38 units) coupled to UV diode array, fluorescence, refraction index, electrochemical, amperometry, light scattering, CAD and mass detector QDa.
  • UHPLC (8): Agilent 1290 and Waters Acquity
  • Agilent Gas chromatography (6) coupled to head-space injection system, with FID/ECD detection
  • Agilent atomic absorption spectrometer
  • Mercury analyzer DMA-80 Milestone
  • UV-visible spectrophotometer (diode array)
  • FTIR Cary 630 Agilent

Immunology

  • WIZARD gamma counter for RIA assays
  • SpectraMax M3/M5 microplate ELISA reader (2)
  • Biotek Epoch / Synergy microplate ELISA reader (2)
  • MESO QuickPlex SQ 120 Meso Scale Discovery for ECLA
  • Guava easyCyte flow cytometer for cell assays
  • Pharmacia PhastSystem high speed electrophoresis
  • Multhiphore II electrophoresis system GE (2)
  • GS-900 calibrated densitometer for electrophoresis
  • Agilent 2100 Bioanalyzer chip electrophoresis
  • Solo VPE UV-visible  spectrophotometer
  • Agilent capillary electrophoresis with LIF detection
  • Beckman PA800S Plus capillary electrophoresis (2)
  • Protein Simple Image isoelectric focusing iCE3
  • QuantStudio 7 Flex real time qPCR
  • King Fisher Flex benchtop sample prep. instrument
  • Cell laboratory fully equipped (2)

Special Lab Instruments

  • Franz cells Crown Glass V-Series manual (1 instruments, 9 cells)
  • Franz cells Phoenix RDS automatic (2 instruments, 12 cells each)
  • Climatic chambers for ICH stability studies and photostability chamber
  • Dissolution test (8), disintegrating test and friability test
  • Particle size Malver Mastersizer 3000
    Cascade impactor for OINDP (Andersen and NGI)
  • Viscosimeter, polarimeter, Karl Fischer (volumetric and coulometric), melting point, osmometer (2)
  • Subvisible particles Pamas (2)
  • TOC analyzer
  • Microbiology laboratory fully equipped
  • Isolator (for sterility testing)
  • Zwick Roel universal testing machines (syringes and autoinjectors)

Other available Instruments

  • Maldi TOF
  • NMR systems
  • SPR (Biacore T200)
  • Circular Dicroism
  • Protein sequencer (Edman degradation)

Download Section

KYMOS-CORPORATE_Downloads_211007-BCN-454-scaled

Get in touch

    Laboratories

    logo of Kymos

    Barcelona
    Spain

    logo of Prolytic

    Frankfurt
    Germany

    logo of Pharmaprogress

    Ancona
    Italy

    Offices

    Paris
    France

    Milano
    Italy

    Branches

    logo of Kymos for KR branch

    Seoul
    Korea